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br Secreted enzymes Only two secreted S aureus enzymes
2024-11-14

Secreted enzymes Only two secreted S. aureus enzymes reportedly induce apoptosis, namely, staphylococcal staphopain B (SspB) and coagulase. SspB selectively cleaved CD11b/CD18 integrin and induced an apoptosis-like cell death in neutrophils and monocytes (Smagur et al., 2009). Neutrophils or mono
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To further evaluate the influence of antibiotics on
2024-11-14

To further evaluate the influence of diacerein on allergy, Russel et al. initiated vancomycin treatment during pregnancy in mice and continued it for several weeks after birth. This resulted in exaggerated OVA-induced allergic inflammation, characterized by higher numbers of lung eosinophils, eleva
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The primary structure of the A
2024-11-14

The primary structure of the Aβ peptide can be divided into four regions based on hydrophobicity. The N-terminal residues 1–16 comprise the first hydrophilic region, which also contains the metal binding site. More specifically, side chain carboxylate of D1 and the side chain nitrogens of H6, H13 an
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Liao and van Linden et al divided the
2024-11-13

Liao [47] and van Linden et al. [48] divided the gap between the N-terminal and C-terminal lobes into a front cleft or pocket, a gate area, and a back cleft. The back pocket corresponds to the gate area and the back cleft. The front cleft includes the Gly-rich loop, the hinge, the linker connecting
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AKT has been shown to be important for G S
2024-11-13

AKT1 has been shown to be important for G1-S checkpoint transition and proliferation, whereas AKT2 regulates cell-cycle exit through its interaction with p21 (Héron-Milhavet et al., 2006). In a recent study in triple negative breast cancer, AKT3, rather than AKT1 activity was most important for cell
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br Role of OCT in histamine
2024-11-13

Role of OCT3 in histamine clearance Histamine is a powerful neuromodulator, as well as a regulator of immune processes and vascular tone in the central nervous system (Gross, 1981; Haas et al., 2008; Jutel et al., 2006). In contrast to 5-HT and the catecholamines, a high-affinity transporter for
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Similarly Dilma et al tried to assess the diagnostic
2024-11-13

Similarly Dilmaç et al. [16] tried to assess the diagnostic value of adenosine deaminase activity in sputum of patients with pulmonary tuberculosis, their aim was to determine and compare sputum ADA activity in pulmonary tuberculosis, lung cancer and chronic obstructive pulmonary disease (COPD) pati
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ACK has been clearly implicated
2024-11-13

ACK1 has been clearly implicated in cancer progression in recent years. A strong correlation between ACK1 gene copy number, protein level and activity have been demonstrated in tumors of different tissue types (Mahajan et al., 2007; van der Horst et al., 2005; Wang et al., 2006). Our western blot an
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In the final set of experiments the dependence of the
2024-11-13

In the final set of experiments, the dependence of the reaction rate on viscosity was determined. The experimental protocol previously used to study the reaction of LOX with AA was used., Reactions of 5-LOX and AA were carried out at different relative viscosities in Tris buffer (25mM, pH 8.0) at 2
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br Discussion Here we focused
2024-11-13

Discussion Here, we focused on seven plant alkaloids extracted from yokukansan. These alkaloids individually inhibited 5-HT-mediated 5-HT3A and 5-HT3AB receptor currents weakly. Simultaneous administration of these alkaloids, however, inhibited the 5-HT3A and 5-HT3AB receptor currents strongly. T
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Recruitment of the Rad BP mediator to
2024-11-13

Recruitment of the Rad9/53BP1 mediator to Betamethasone involves multiple pathways (Fig. 2). In unperturbed conditions, Rad9 is already bound to chromatin via interaction between its Tudor domain and methylated histone H3 at lysine 79 [82], [83], [84], [85]. This constitutive Rad9 recruitment to ch
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On the other hand there were only a few cases
2024-11-13

On the other hand, there were only a few cases that expressed DA2R in our study. Additionally, in the cases whose ACTH-secreting pituitary adenomas expressed DA2R, the ratio of positive staining INCB024360 analogue was very low. This suggests that dopamine agonists may be less effective in canine Cu
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br In vivo visualization of aromatase with positron emission
2024-11-13

In vivo visualization of aromatase with positron emission tomography (PET) Positron emission tomography (PET) utilizes the high 143 93 photons formed during the annihilation of positrons to detect the changes in the amount and localization of injected radiopharmaceuticals in the living body (rec
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Plasma apelin levels predict the major cardiovascular event
2024-11-12

Plasma apelin levels predict the major cardiovascular event after percutaneous coronary intervention in patients with ST elevation myocardial infarction (STEMI), and adverse events are higher in patients with lower plasma apelin levels [75]. Apelin and its receptor are markedly upregulated in the he
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BIBR 1532 Introduction Enzymatic browning degrades quality s
2024-11-12

Introduction Enzymatic browning degrades quality, safety, and nutritional values of various fruits or vegetable products. For example, the color of apple or potato is generally yellowish, representing freshness. However, they are extremely susceptible to enzymatic browning because of abundant polyp
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